One drop in each eye, repeatable once after 2 to 3 hours for an effect lasting up to 8 hours; daily or as needed
A low-concentration, preservative-free pilocarpine: the 0.4% strength is chosen to limit brow ache and dim vision
Contraindications
Hypersensitvity
Available Forms
Pilocarpine hydrochloride ophthalmic solution 0.4% in single-dose vials.
Mechanism of Action
Pilocarpine hydrochloride is a cholinergic muscarinic agonist which activates muscarinic receptors located at smooth muscles such as the iris sphincter muscle and ciliary muscle. QLOSI contracts the iris sphincter muscle, constricting the pupil to enhance the depth of focus and improve near visual acuity while maintaining some pupillary response to light.
Warnings & Precautions
Blurred vision: advise patients not to drive or operate machinery when vision is not clear, and to take care with night driving.
Retinal detachment has been reported with miotics; advise patients to report a sudden loss of vision at once.
Iritis: not recommended in active iritis.
Remove contact lenses before instillation.
Common Side Effects
Most common adverse reactions (5% to 8%) are instillation site pain and headaches.
Pregnancy & Lactation
Pregnancy: No adequate and well-controlled studies in pregnant women.
GoodRx
Available Forms
Mechanism of Action
Pregnancy & Lactation
Pediatric Use