Approved uses
Ocular itching associated with allergic conjunctivitis
1 drop in each affected eye BID, approximately 8 hours apart
Itch relief begins within 15 minutes of dosing and lasts about 8 hours.
Contraindications
None.
Available FormsOphthalmic solution, 0.24% (2.4 mg/mL), 5 mL fill in a 7.5 mL bottle, 7.5 mL fill in a 10 mL bottle, carton of 30 single-use 0.2 mL containers
Mechanism of ActionTopical histamine-1 (H1) receptor antagonist that blocks histamine-mediated ocular itching. In vitro binding shows no measurable affinity for receptors other than H1, with negligible anticholinergic and antiserotonergic activity in animal models.
Warnings & Precautions
- Lens wear: Remove lenses before instillation and reinsert 10 minutes afterward; the benzalkonium chloride preservative may be absorbed by soft lenses. Lenses should not be worn while the eye is red.
Pregnancy & Lactation
Pediatric Use