iDose® TR
GoodRxTravoprost 75 mcg · intracameral implant
Antiglaucoma, Injections & Implants
Approved uses
Open-angle glaucoma or ocular hypertension
A single travoprost implant administered intracamerally under aseptic conditions
Removes the daily-drop adherence problem for a prostaglandin, which is the usual reason pressure control fails
Contraindications
Ocular or periocular infections Corneal endothelial dystrophy Prior corneal transplantation Hypersensitivity.
Available FormsTravoprost intracameral implant pre-loaded in a sterile single-dose inserter.
Mechanism of ActionTravoprost free acid, a prostaglandin analog is a selective FP prostanoid receptor agonist, which is believed to reduce IOP by increasing uveoscleral outflow. The exact mechanism of action is unknown at this time.
Warnings & Precautions
- Iridocorneal angles: use with caution in narrow angles or other angle abnormalities.
- Device dislocation: monitor routinely to confirm the implant remains at the site of administration.
- Corneal adverse reactions, including corneal endothelial cell loss, have been reported.
- May cause increased brown pigmentation of the iris, which is likely to be permanent.
Common Side Effects
the most common ocular adverse reactions reported in 2% to 6% of patients were increases in intraocular pressure, iritis, dry eye, and visual field defects.
Pregnancy & LactationPregnancy: No adequate and well-controlled studies in pregnant women. Subcutaneous travoprost in animals produced adverse effects at exposures far above the clinical one.
Lactation: Unknown whether travoprost is present in human milk.
Pediatric UseThe safety and effectiveness of iDose TR have not been established in pediatric patients.