Triesence®
GoodRxTriamcinolone Acetonide 40 mg/mL · injectable suspension
Steroid, Injections & Implants
Approved uses
Sympathetic ophthalmia, temporal arteritis, uveitis, and ocular inflammation unresponsive to topical steroids
4 mg (100 microlitres of 40 mg/mL) intravitreally, with further doses as needed over the course of treatment
Visualization of the vitreous during vitrectomy
1 to 4 mg (25 to 100 microlitres of 40 mg/mL) intravitreally
A different job from the anti-inflammatory use: the particles make the vitreous visible to the surgeon
Contraindications
Corticosteroids are contraindicated in patients with systemic fungal infections. Triamcinolone is contraindicated in patients who are hypersensitive to corticosteroids or any components of this product. Rare instances of anaphylactoid reactions have occurred in patients receiving corticosteroid therapy. Hypersensitivity to triamcinolone or any component of this product.
Available Forms40 mg/mL triamcinolone acetonide injectable suspension, 1 mL vial.
Mechanism of ActionNaturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs, such as prednisolone and triamcinolone are primarily used for their anti-inflammatory effects in disorders of many organ systems. Triamcinolone acetonide possesses glucocorticoid activity typical of this class of drug, but with little or no mineralocorticoid activity.
Warnings & Precautions
- Do not administer intravenously.
- Ophthalmic effects may include cataract, infection and glaucoma; monitor intraocular pressure.
- Hypothalamic-pituitary-adrenal axis suppression, Cushing's syndrome and hyperglycaemia can follow corticosteroid use.
- May mask signs of infection or worsen an existing one, including latent amebiasis and ocular herpes simplex.
Common Side Effects
The most common dose administered within these trials was triamcinolone acetonide 4 mg administered as primary or adjunctive therapy primarily as a single injection.
Pregnancy & LactationPregnancy: Pregnancy Category D. Human cohort and case-control studies suggest maternal corticosteroid use in the first trimester raises the risk of cleft lip with or without cleft palate.
Lactation: Systemically administered corticosteroids appear in human milk and could suppress growth or endogenous steroid production.
Pediatric UseThe efficacy and safety of corticosteroids in the pediatric population are based on the well established course of effect of corticosteroids which is similar in pediatric and adult populations. The adverse effects of corticosteroids in pediatric patients are similar to those in adults.