Triesence (Triamcinolone Acetonide 40 mg/mL)

Approved uses

Sympathetic ophthalmia, temporal arteritis, uveitis, and ocular inflammation unresponsive to topical steroids

4 mg (100 microlitres of 40 mg/mL) intravitreally, with further doses as needed over the course of treatment

Visualization of the vitreous during vitrectomy

1 to 4 mg (25 to 100 microlitres of 40 mg/mL) intravitreally

A different job from the anti-inflammatory use: the particles make the vitreous visible to the surgeon

Contraindications

Corticosteroids are contraindicated in patients with systemic fungal infections. Triamcinolone is contraindicated in patients who are hypersensitive to corticosteroids or any components of this product. Rare instances of anaphylactoid reactions have occurred in patients receiving corticosteroid therapy. Hypersensitivity to triamcinolone or any component of this product.

Available Forms

40 mg/mL triamcinolone acetonide injectable suspension, 1 mL vial.

Mechanism of Action

Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs, such as prednisolone and triamcinolone are primarily used for their anti-inflammatory effects in disorders of many organ systems. Triamcinolone acetonide possesses glucocorticoid activity typical of this class of drug, but with little or no mineralocorticoid activity.